71. Widening the Therapeutic Perspectives of Clofazimine by its Loading in Sulfobutylether β-Cyclodextrin Nanocarriers: Nanomolar IC50 Values against MDR S. epidermidis
Wankar, J., Bonvicini, F., Benkovics, G.,Marassi, V., Malanga, M.,Fenyvesi, E.,Gentilomi, G.A.,Reschiglian, P., Roda, B.,Manet, I.

Molecular Pharmaceutics, 2018, in press. DOI: 10.1021/acs.molpharmaceut.8b00321

 
70. Mannoside and 1,2-mannobioside β-cyclodextrin-scaffolded NO-photodonors for targeting antibiotic resistant bacteria
Cutrone, G., Benkovics, G., Malanga, M., (...), García-Fuentes, L., Vargas-Berenguel, A.
Carbohydrate Polymers, 2018, 199, 649-660.DOI: 10.1016/j.carbpol.2018.07.018
 
69. Confined photo-release of nitric oxide with simultaneous two-photon fluorescence tracking in a cellular system
Thomsen, H., Marino, N., Conoci, S., Sortino, S., Ericson, M.B.
 Scientific Reports 2018, 8(1), 9753. DOI: 10.1038/s41598-018-27939-4
 
68. Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach
Pancani, E., Menendez-Miranda, M.,Pastor, A., Brisset, F., Bernet-Camard, M.-F., Desmaële, D., Gref, R.
Acta Pharmaceutica Sinica B, 2018, 8(3), 4290-431.DOI: 10.1016/j.apsb.2018.03.008
 
67. High-Resolution Label-Free Detection of Biocompatible Polymeric Nanoparticles in Cells
Pancani, E., Mathurin, J., Bilent, S., Bernet-Camard, M.-F.Dazzi, A., Deniset-Besseau, A., Gref, R.
Particle and Particle Systems Characterization, 2018, 35(3), Article No 1700457. DOI: 10.1002/ppsc.201700457
 
 
66. Effect of β- and γ-cyclodextrins and their methylated derivatives on the degradation rate of benzylpenicillin
Popielec, A., Agnes, M., Yannakopoulou, K., Fenyvesi, É., Loftsson, T.
 
 65. Fluorescence imaging of antibiotic clofazimine encapsulated within mesoporous silica particle carriers: relevance to drug delivery and the effect on its release kinetics
Lorenzo Angiolini, Sabrina Valetti, Boiko Cohen, Adam Feiler and Abderrazzak Douhal
Phys. Chem. Chem.Phys. 2018, 20, 11899-11911. doi:10.1039/C7CP08328A
 
64. High-Resolution Label-Free Detection of Biocompatible Polymeric Nanoparticles in Cells
Elisabetta Pancani , Jérémie Mathurin , Sylvie Bilent , Marie-Françoise Bernet-Camard , Alexandre Dazzi , Ariane Deniset-Besseau , Ruxandra Gref
Particle and Particle Systems Characterization, 2018, doi:10.1002/ppsc.201700457
 
63. Proteomics of Mycobacterium infection: Moving towards a Better Understanding of Pathogen-Driven immunomodulation
Eik Hoffmann, Arnaud Machelart, Ok-Ryul Song and Priscille Brodin
Frontiers in Immunology, 2018, 9, article 86.DOI:10.3389/fimmu.2018.00086

 

62. Self-assembled cyclodextrin-based nanoparticles for meropenem stabilization
Popielec, A., Agnes, M., Yannakopoulou, K., Fenyvesi, É., Loftsson, T.
Journal of Drug Delivery Science and Technology, 2018, 45, 20-27DOI: 10.1016/j.jddst.2018.02.018

 

61. Monitoring the Release of a NO Photodonor from Polymer Nanoparticles via Förster Resonance Energy Transfer and Two-Photon Fluorescence Imaging
C. Conte,A. Fraix, H. Thomsen, F. Ungaro,V. Cardile,A. C. E. Graziano, M. B. Ericson, F. Quaglia and S. Sortino
J. Mater. Chem. B, 2018, 6(2),  249-256, DOI: 10.1039/c7tb02781h

 

60. Photoactivity of New Octacationic Magnesium(II) and Zinc(II) Porphyrazines in a Water Solution and G-Quadruplex Binding Ability of Differently Sized Zinc(II) Porphyrazines
, , , , , , and
Inorg. Chem., 2017, 56 (21), 12795–12808. doi: 10.1021/acs.inorgchem.7b01557
 
59. Synthesis, analytical characterization and capillary electrophoretic use of the single-isomer heptakis-(6-O-sulfobutyl)-beta-cyclodextrin
Milo Malanga, Ida Fejős, Erzsébet Varga, Gábor Benkovics, András Darcsi, Julianna Szemán, Szabolcs Béni
J. Chromatogr. A, 2017, 1514, 127-133. doi:10.1016/j.chroma.2017.07.069
 
58. Spontaneous Self-Assembly of Polymeric Nanoparticles in Aqueous Media: New Insights From Microfluidics, In Situ Size Measurements, and Individual Particle Tracking
Li, X., Salzano, G., Zhang, J., Gref, R.
J. Pharm. Sci. 2017, 395-401. https://doi.org/10.1016/j.xphs.2016.09.024
 
57. A Molecular Hybrid for Mitochondria-Targeted NO Photodelivery
F. Sodano, E. Gazzano,A. Fraix, B. Rolando, L. Lazzarato, M. Russo, M. Blangetti, C.Riganti, R. Fruttero, A. Gasco and S. Sortino
ChemMedChem 2017, accepted. DOI: 10.1002/cmdc.201700608

 

56. Host–pathogen systems for early drug discovery against tuberculosis
Valentin Trofimov , Joana Costa-Gouveia , Eik Hoffmann , Priscille Brodin
Current Opinion in Microbiology, 2017, 39, 143-151. doi:10.1016/j.mib.2017.11.017

 

55. Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling
C. J. Queval, O.-R. Song, J.-P. Carralot, J.-M. Saliou, A. Bongiovanni, G. Deloison, N. Deboosère, S. Jouny, R. Iantomasi, V. Delorme, A.-S. Debrie, S.-J. Park, J. Costa Gouveia, S. Tomavo, R. Brosch, A. Yoshimura, E. Yeramian, P. Brodin
Cell Reports, 2017, 20(13):3188-3198, http://dx.doi.org/10.1016/j.celrep.2017.08.101

 

54. Characterization of a single‐isomer carboxymethyl‐beta‐cyclodextrin in chiral capillary electrophoresis

Ida Fejős, Erzsébet Varga, Gábor Benkovics, Milo Malang, Tamás Sohajda, Julianna Szemán, Szabolcs Béni

Electrophoresis, 2017, 38, 1869-1877. DOI:10.1002/elps.201700004

 

53. The ‘Visualized’ macrocycles: Chemistry and application of fluorophore tagged cyclodextrins

Gábor Benkovics , Milo Malanga , Éva Fenyvesi

Int. J. Pharm. 2017, 531, 689-700, doi:10.1016/j.ijpharm.2017.04.035

 

52. Cyclodextrin-Modified inorganic materials for the construction of nanocarriers
G. Cutrone G, Casas-Solvas JM1, Vargas-Berenguel A2
Int. J. Pharm. 2017 15;531(2):621-639. doi: 10.1016/j.ijpharm.2017.06.080

 

51. New insights into the degradation mechanism of metal-organic frameworks drug carriers
X. Li, L. Lachmanski, S. Safi, S. Sene, C. Serre, J. M. Grenèche, J. Zhang, and R. Gref
Sci. Rep. 2017; 7: 13142. doi:10.1038/s41598-017-13323-1

 

50. Moisture resistant and biofriendly CD-MOF nanoparticles abtained via cholesterol shielding
V. SinghT. GuoH. XuL. WuJ. GuC. WuR. Gref,Jiwen Zhang

 

49. A non-covalent “click chemistry” strategy to efficiently coat highly porous MOF nanoparticles with a stable polymeric shell
A. Aykac, M. Noiray, M. Malanga, V. Agostoni, J. -M. Casas-Solvas, E. Fenyvesi, R. Gref, A. Vargas-Berenguel

 

48. Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells
V. Rodriguez-Ruiz, A. Maksimenko, G. Salzano, M. Lampropoulou, Y. G. Lazarou, V. Agostoni, P. Couvreur, R. Gref, K. Yannakopoulou
Scientific Reports 7, 2017, 8353, . doi: 10.1038/41598-017-08727-y

 

47. Molecular recognition of N-acetyltryptophan enantiomers by β-cyclodextrin
S. D. Chatziefthimiou, M. Inclán, P. Giastas, A. Papakyriakou, K. Yannakopoulou, I. M. Mavridis
Beilstein J. Org. Chem. 2017, 13, 1572–1582. doi:10.3762/bjoc.13.157

 

46. Multivalent mesoporous silica nanoparticles photo-delivering nitric oxide with carbon dots as fluorescent reporters
D. Afonso, S. Valetti,A. Fraix, C. Bascetta, S. Petralia, S. Conoci, A. Feilerand S. Sortino
Nanoscale, 2017, 9(36), 13404-13408. DOI: 10.1039/c7nr04832g

 

45. Bare and Effective Charge of Mesoporous Silica Particles
S. Valetti, A. Feiler, M.  Trulsson


44. Host-directed therapies offer novel opportunities for the fight against tuberculosis
A. Machelart, O.-R. Song, E. Hoffman, P. Brodin
Drug Discov. Today, in print, https://doi.org/10.1016/j.drudis.2017.05.005

 

43. Cyclodextrin-based metal-organic frameworks particles as efficient carriers for lansoprazole: Study of morphology and chemical composition of individual particles
Li, X., Guo, T., Lachmanski, L., Manoli, F., Menendez-Miranda, M., Manet, I., Guo, Z., Wu, L., Zhang, J., Gref, R.

 

42. Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles
J. Costa-Gouveia, E. Pancani, S. Jouny, A. Machelart, V. Delorme, G. Salzano, R. Lantomasi, C. Piveteau, C.
J. Queval, O.-R. Song, M. Flipo, B.t Deprez, J.-P. Saint-André, J. Hureaux, L. Majlessi, N. Willand, A. Baulard, P. Brodin, R. Gref
Scientific Reports, 7: 5390, DOI:10.1038/s41598-017-05453-3
 
41. Effects of cyclodextrins on the chemical stability of drugs
A. Popielec, Th. Loftsson
 
40. Cyclodextrin-Modified Inorganic Materials for the Construction of Nanocarriers
G. Cutrone, J. M. Casas-Solvas, A. Vargas-Berenguel
 
39. Design, Synthesis and Antibacterial Activity of a Multivalent Polycationic Calix[4]arene‒NO Photodonor Conjugate
G. M. L. Consoli, Ivana Di Bari, A. R. Blanco, A. Nostro, M. D’Arrigo, V. Pistarà and S. Sortino
 
38. Delivery of cyclodextrin polymers to bacterial biofilms — An exploratory study using rhodamine labelled cyclodextrins and multiphoton microscopy
Hanna Thomsen, Gabor Benkovics, Eva Fenyvesi, Anne Farewell, Milo Malanga, Marica. B. Ericson
 
37. Formation, characterization and pH dependence of rifampicin:heptakis(2,6-di-O-methyl)-β-cyclodextrin complexes
Lorenzo Angiolini, Marco Agnes, Boiko Cohen, Konstantina Yannakopoulou, Abderrazzak Douhal
 
36. Cyclodextrin-mesoporous silica particle composites for controlled antibiotic release. A proof of concept toward colon targeting
Louise Stjern,Sandra Voittonen, Rahel Weldemichel, Sofia Thuresson, Marco Agnes, Gabor Benkovics, Éva Fenyvesi, Milo Malanga, Konstantina Yannakopoulou, Adam Feiler,,Sabrina Valetti
 
35. Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery
 
Nanoscale, advance article, DOI:10.1039/C6NR07593B
 
34. Efficient loading of ethionamide in cyclodextrin-based carriers offers enhanced solubility and inhibition of drug crystallization
Jitendra Wankar, Giuseppina Salzano, Elisabetta Pancani, Gabor Benkovics, Milo Malanga, Francesco Manoli, Ruxandra Gref, Eva Fenyvesi, Ilse Manet
 
33. A novel nonmetal-containing nitric oxide releaser activatable with single-photon green light
Salvatore Sortino, Marco Blangetti, Aurore Fraix, Loretta Lazzarato, Elisabetta Marini, Barbara Rolando, Federica Sodano, Roberta Fruttero and Alberto Gasco
Chem. Eur. J. in press 2017 DOI: 10.1002/chem.201701889
 
32. Cyclodextrin-based nanocarriers containing a synergic drug combination: a potential formulation for pulmonary administration of antitubercular drugs
Giuseppina Salzano, Jitendra Wankar, Stefano Ottani, Baptiste Villemagne, Alain R. Baulard, Nicolas Willand, Priscille Brodin, Ilse Manet,Ruxandra Gref
 
31. A Multifunctional β-Cyclodextrin-Conjugate Photodelivering Nitric Oxide with Fluorescence Reporting
Gábor Benkovics, Marta Perez-Lloret, Damien Afonso, András Darcsi, Szabolcs Béni, Éva Fenyvesi, Milo Malanga, Salvatore Sortino
 
30. Design and evaluation of artificial receptors for the reversal of neuromuscular block
Tamás Sohajda, Ákos Fábián, Kata Tuza, Milo Malanga, Gábor Benkovics, Béla Fülesdi, Edömér Tassonyi, Lajos Szente
 
29. Designed positively charged cyclodextrin hosts with enhanced binding of penicillins as carriers for the delivery of antibiotics: the case of oxacillin
M. Agnes, A. Thanassoulas, P. Stavropoulos, G. Nounesis, G. Miliotis, V. Miriagou, E. Athanasiou, G. Benkovics, M. Malanga, K. Yannakopoulou
Int. J. Pharm. 2017, 531(2), 480-491, doi.org/10.1016/j.ijpharm.2017.04.080
 
28. Novel β-cyclodextrin–eosin conjugates
Gábor Benkovics, Damien Afonso, András Darcsi, Szabolcs Béni, Sabrina Conoci, Éva Fenyvesi, Lajos Szente, Milo Malanga and Salvatore Sortino
 
27. Targeted Photodynamic Therapy with a Folate/Sensitizer Assembly Produced from Mesoporous Silica
Chunfang Zhou, Damien Afonso, Sabrina Valetti, Adam Feiler, Venera Cardile, Adriana C. E. Graziano, Sabrina Conoci and Salvatore Sortino
 
26. Mesoporous silica particles as a lipophilic drug vehicle investigated by fluorescence lifetime imaging
 
25. Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections
Valetti, S.; Xia, X.; Costa-Gouveia, J.; Brodin, P.; Bernet-Camard, M.-F.; Andersson, M.; Feiler, A., 
Nanomedicine 2017. doi:10.2217/nnm-2016-0364
 
24. How can nanoparticles contribute to antituberculosis therapy?
Costa-Gouveia J, Aínsa JA, Brodin P, Lucía A.
Drug Discov Today, 2017, Mar;22(3), 600-607 DOI: 10.1016/j.drudis.2017.01.011
 
23. Spontaneous Self-Assembly of Polymeric Nanoparticles in Aqueous Media: New Insights From Microfluidics, In Situ Size Measurements, and Individual Particle Tracking
Li X, Salzano G, Zhang J, Gref R
J. Pharm. Sci., 2017, 106(1), 395-401;http://dx.doi.org/10.1016/j.xphs.2016.09.024

 

22. The “visible” cyclodextrins: Synthesis and cell biological application of fluorescent-tagged cyclodextrins
Benkovics, G., Malanga, M., Fenyvesi, É.
Magyar Kémiai Folyóirat, 2016, 122(2-4), 76-82
 
21. Light-Regulated NO Release as a Novel Strategy To Overcome Doxorubicin Multidrug Resistance
K. Chegaev,  Aurore Fraix, Elena Gazzano,  Gamal Eldein F. Abd-Ellatef, M. Blangetti, B. Rolando, S. Conoci, C. Riganti, R. Fruttero, A. Gasco and S.  Sortino
 
20. Supramolecular activation of the photodynamic properties of porphyrinoid photosensitizers by calix[4]arene nanoassemblies
Ivana Di Bari, Aurore Fraix, Roberta Picciotto, Anna R. Blanco, Salvatore Petralia,Sabrina Conoci,  Giuseppe Granata, Grazia M. L. Consoli and Salvatore Sortino
RSC Adv., 2016, DOI: 10.1039/C6RA23492E.
 
19. Comparative evaluation of the chiral recognition potential of single-​isomer sulfated beta-cyclodextrinsynthesis intermediates in non-​aqueous capillary electrophoresis.
Fejos Ida; Darcsi Andras; Varga Erzsebet; Malanga Milo; Fenyvesi Eva; Sohajda Tamas; Szente Lajos; Benkovics Gabor; Beni Szabolcs
Journal of Chromatography A, Available online 15 July 2016, doi:10.1016/j.chroma.2016.07.033
 
18.Graphene oxide nanohybrid photoreleasing nitric oxide
Nino Marino, Salvatore Petralia, Marta Perez-Lloret, Jiri Mosinger, Sabrina Conoci  and Salvatore Sortino
 
17. Single-isomer carboxymethyl-γ-cyclodextrin as chiral resolving agent for capillary electrophoresis
Gábor Benkovics, Ida Fejős, András Darcsi, Erzsébet Varga, Milo Malanga, Éva Fenyvesi, Tamás Sohajda, Lajos Szente, Szabolcs Béni, Julianna Szemán
J. Chromatogr. A,  accepted, Available online 1 July 2016
 
16. Photo-antimicrobial polymeric films releasing nitric oxide with fluorescent reporting under visible light
Nino Marino, Marta Perez-Lloret,Anna R. Blanco Alessandro Venuta, Fabiana Quagliaand Salvatore Sortino
J. Mater. Chem. B,accepted
 
15. A bactericidal calix[4]arene-based nanoconstruct with amplified NO photorelease
Ivana Di Bari, Roberta Picciotto, Giuseppe Granata, Anna R. Blanco,Grazia M. L. Consoliand Salvatore Sortino
Organic & Biomolecular Chemistry, accepted
 
14. New synthetic strategies for xanthene-dye-appended cyclodextrins  
M. Malanga, A. Darcsi, M. Balint, G. Benkovics, T. Sohajda, S. Beni  
Beilstein Journal of Organic Chemistry 2016, 12, 537-548. DOI: 10.3762/bjoc.12.53
 
13. Small is beautiful: Surprising nanoparticles
D. Duchêne, . Gref
Int. J.Pharm. 2016, 502(1), 219-231. doi.org/10.1016/j.ijpharm.2016.02.016
 
12. Effect of cyclodextrins on the degradation rate of benzylpenicillin
A.Popielec, E. Fenyvesi, K. Yannakopoulou and T. Loftsson
 Die PHARMAZIE2016, 71, 68–75. DOI: 10.1691/ph.2016.5114
 
11. Multilamellar Nanoparticles Self-Assembled from Opposite Charged Blends: Insights from Mesoscopic Simulation
S. Nie, X. Zhang, R. Gref, P. Couvreur, Y. Qian, L. Zhang
 
10. Polystyrene nanofiber materials for visible light-driven dual antibacterial action via simultaneous photogeneration
of NO and 1O2
J. Dolanský, P. Henke, P. Kubát, A. Fraix, S. Sortino and J. Mosinger
ACS Mater. Interf. Sci. DOI: 10.1021/acsami.5b06233
 
9. Towards an optimized treatment of intracellular bacteria infections: input of nanoparticulate drug delivery systems
C. Ladavière, R. Gref
Nanomedicine,DOI:10.2217/nnm.15.128 Invited review article.
 
8. Efficient “green” encapsulation of a highly hydrophilic anticancer drug in Metal-organic frameworks nanoparticles
V. Rodriguez-Ruiza, A. Maksimenko, R. Anand, S. Monti, V. Agostoni, P. Couvreur, M. Lampropoulou, K. Yannakopoulou, R. Gref
 J. Drug Targeting, 2015, 23(7-8), 759-767. DOI:10.3109/1061186X.2015.1073294Invited article in special issue honoring Prof. R. Langer for his lifetime achievements in the biomedical field.
 
7. Synthesis, characterization and photo-bactericidal activity of silanized xanthene-modified bacterial cellulose
membranes
H. Hettegger, M. Gorfer, S. Sortino, A. Fraix, D. Bandian, C. Rohrer,  W. Harreither, A. Potthast, T. Rosenau
Cellulose, Published online Sept 4, 2015. DOI 10.1007/s10570-015-0715-y
 
6. Anionic cyclodextrins as versatile hosts for pharmaceutical nanotechnology: Synthesis, drug delivery, enantioselectivity, contrast agents for MRI
I. M. Mavridis, K. Yannakopoulou
 
5. Cyclodextrins in the Battle against Antibiotic Resistant Microorganisms: Mimicking Cyclic Peptide Antibiotics
G. Benkovics
 
4. Cyclodextrins, blood-brain barrier, and treatment of neurological diseases
M. Vecsernyés, F. Fenyvesi, I. Bácskay, M.A. Deli, L. Szente, E. Fenyvesi
Archives of Medical Research 2014, 45, 711-729 DOI: http://dx.doi.org/10.1016/j.arcmed.2014.11.020
 
3. A multicomponent gel for nitric oxide photorelease with fluorescent reporting
A. Fraix, N. Kandoth, R. Gref, and S. Sortino
Asian J. Org. Chem. 2015, 4(3), 256-261  DOI: 10.1002/ajoc.201402267
 
2.  A “green” strategy to construct non-covalent, stable and bioactive coatings on porous MOF nanoparticles
V. Agostoni, P. Horcajada, M. Noiray, M. Malanga, A. Aykaç, L. Jicsinszky, A. Vargas-Berenguel, N. Semiramoth, S. Daoud-Mahammed, V. Nicolas, C. Martineau, F. Taulelle, J. Vigneron, A. Etcheberry, C. Serre, R. Gref
 
1. Fighting against bacterial resistance to penicillins with CDs
 E. Fenyvesi