55. Monitoring the Release of a NO Photodonor from Polymer Nanoparticles via Förster Resonance Energy Transfer and Two-Photon Fluorescence Imaging

C. Conte,A. Fraix, H. Thomsen, F. Ungaro,V. Cardile,A. C. E. Graziano, M. B. Ericson, F. Quaglia and S. Sortino

J. Mater. Chem. B, 2017 Accepted for publication

 

54. A Molecular Hybrid for Mitochondria-Targeted NO Photodelivery

F. Sodano, E. Gazzano,A. Fraix, B. Rolando, L. Lazzarato, M. Russo, M. Blangetti, C.Riganti, R. Fruttero, A. Gasco and S. Sortino

ChemMedChem 2017, accepted. DOI: 10.1002/cmdc.201700608

 

53. Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

C. J. Queval, O.-R. Song, J.-P. Carralot, J.-M. Saliou, A. Bongiovanni, G. Deloison, N. Deboosère, S. Jouny, R. Iantomasi, V. Delorme, A.-S. Debrie, S.-J. Park, J. Costa Gouveia, S. Tomavo, R. Brosch, A. Yoshimura, E. Yeramian, P. Brodin

Cell Reports, 2017, 20(13):3188-3198, http://dx.doi.org/10.1016/j.celrep.2017.08.101

 

52. Cyclodextrin-Modified inorganic materials for the construction of nanocarriers

G. Cutrone G, Casas-Solvas JM1, Vargas-Berenguel A2

Int. J. Pharm. 2017 15;531(2):621-639. doi: 10.1016/j.ijpharm.2017.06.080

 

51. New insights into the degradation mechanism of metal-organic frameworks drug carriers

X. Li, L. Lachmanski, S. Safi, S. Sene, C. Serre, J. M. Grenèche, J. Zhang, and R. Gref

Sci. Rep. 2017; 7: 13142. doi:10.1038/s41598-017-13323-1

 

50. Moisture resistant and biofriendly CD-MOF nanoparticles abtained via cholesterol shielding

V. SinghT. GuoH. XuL. WuJ. GuC. WuR. Gref,Jiwen Zhang

53 (66), 9246-9249. doi: 10.1039/C7CC03471G

 

49. A non-covalent “click chemistry” strategy to efficiently coat highly porous MOF nanoparticles with a stable polymeric shell

A. Aykac, M. Noiray, M. Malanga, V. Agostoni, J. -M. Casas-Solvas, E. Fenyvesi, R. Gref, A. Vargas-Berenguel

 

48. Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells

V. Rodriguez-Ruiz, A. Maksimenko, G. Salzano, M. Lampropoulou, Y. G. Lazarou, V. Agostoni, P. Couvreur, R. Gref, K. Yannakopoulou

Scientific Reports 7, 8353. doi: 10.1038/41598-017-08727-y

 

47. Molecular recognition of N-acetyltryptophan enantiomers by β-cyclodextrin

S. D. Chatziefthimiou, M. Inclán, P. Giastas, A. Papakyriakou, K. Yannakopoulou, I. M. Mavridis

Beilstein J. Org. Chem. 2017, 13, 1572–1582. doi:10.3762/bjoc.13.157

 

46. Multivalent mesoporous silica nanoparticles photo-delivering nitric oxide with carbon dots as fluorescent reporters

D. Afonso, S. Valetti,A. Fraix, C. Bascetta, S. Petralia, S. Conoci, A. Feilerand S. Sortino

Nanoscale, 2017 in press

 

45. Bare and Effective Charge of Mesoporous Silica Particles

S. Valetti, A. Feiler, M.  Trulsson

Langmuir 2017, doi: 10.1021/acs.langmuir.7b01135


44. Host-directed therapies offer novel opportunities for the fight against tuberculosis

A. Machelart, O.-R. Song, E. Hoffman, P. Brodin

Drug Discov. Today, in print, https://doi.org/10.1016/j.drudis.2017.05.005

 

43. Cyclodextrin-based metal-organic frameworks particles as efficient carriers for lansoprazole: Study of morphology and chemical composition of individual particles

Li, X., Guo, T., Lachmanski, L., Manoli, F., Menendez-Miranda, M., Manet, I., Guo, Z., Wu, L., Zhang, J., Gref, R.

Int. J. Pharm. in print, https://doi.org/10.1016/j.ijpharm.2017.05.056

 

42. Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

J. Costa-Gouveia, E. Pancani, S. Jouny, A. Machelart, V. Delorme, G. Salzano, R. Lantomasi, C. Piveteau, C.
J. Queval, O.-R. Song, M. Flipo, B.t Deprez, J.-P. Saint-André, J. Hureaux, L. Majlessi, N. Willand, A. Baulard, P. Brodin, R. Gref

Scientific Reports, 7: 5390, DOI:10.1038/s41598-017-05453-3

 

41. Effects of cyclodextrins on the chemical stability of drugs

A. Popielec, Th. Loftsson

Int. J. Pharm. in print, https://doi.org/10.1016/j.ijpharm.2017.06.009

 

40. Cyclodextrin-Modified Inorganic Materials for the Construction of Nanocarriers

G. Cutrone, J. M. Casas-Solvas, A. Vargas-Berenguel

Int. J. Pharm. Acceptedhttps://doi.org/10.1016/j.ijpharm.2017.06.080

 

39. Design, Synthesis and Antibacterial Activity of a Multivalent Polycationic Calix[4]arene‒NO Photodonor Conjugate

G. M. L. Consoli, Ivana Di Bari, A. R. Blanco, A. Nostro, M. D’Arrigo, V. Pistarà and S. Sortino

ACS Med. Chem. Lett. 2017, http://pubs.acs.org/doi/10.1021/acsmedchemlett.7b00228

 

38. Delivery of cyclodextrin polymers to bacterial biofilms — An exploratory study using rhodamine labelled cyclodextrins and multiphoton microscopy

Hanna Thomsen, Gabor Benkovics, Eva Fenyvesi, Anne Farewell, Milo Malanga, Marica. B. Ericson

Int. J. Pharm. in print, https://doi.org/10.1016/j.ijpharm.2017.06.011

 

37. Formation, characterization and pH dependence of rifampicin:heptakis(2,6-di-O-methyl)-β-cyclodextrin complexes

Lorenzo Angiolini, Marco Agnes, Boiko Cohen, Konstantina Yannakopoulou, Abderrazzak Douhal

Int. J. Pharm. in print, https://doi.org/10.1016/j.ijpharm.2017.06.015

 

36. Cyclodextrin-mesoporous silica particle composites for controlled antibiotic release. A proof of concept toward colon targeting

Louise Stjern,Sandra Voittonen, Rahel Weldemichel, Sofia Thuresson, Marco Agnes, Gabor Benkovics, Éva Fenyvesi, Milo Malanga, Konstantina Yannakopoulou, Adam Feiler,,Sabrina Valetti

Int. J. Pharm. accepted,  https://doi.org/10.1016/j.ijpharm.2017.05.062

 

35. Composite CD-MOF nanocrystals-containing microspheres for sustained drug delivery

 

Nanoscale, advance article, DOI:10.1039/C6NR07593B

 

34. Efficient loading of ethionamide in cyclodextrin-based carriers offers enhanced solubility and inhibition of drug crystallization

Jitendra Wankar, Giuseppina Salzano, Elisabetta Pancani, Gabor Benkovics, Milo Malanga, Francesco Manoli, Ruxandra Gref, Eva Fenyvesi, Ilse Manet

 

33. A novel nonmetal-containing nitric oxide releaser activatable with single-photon green light

Salvatore Sortino, Marco Blangetti, Aurore Fraix, Loretta Lazzarato, Elisabetta Marini, Barbara Rolando, Federica Sodano, Roberta Fruttero and Alberto Gasco

Chem. Eur. J. in press 2017 DOI: 10.1002/chem.201701889

 

32.Cyclodextrin-based nanocarriers containing a synergic drug combination: a potential formulation for pulmonary administration of antitubercular drugs

Giuseppina Salzano, Jitendra Wankar, Stefano Ottani, Baptiste Villemagne, Alain R. Baulard, Nicolas Willand, Priscille Brodin, Ilse Manet,Ruxandra Gref

Int. J. Pharm. accepted, https://doi.org/10.1016/j.ijpharm.2017.05.030

 

31. A Multifunctional β-Cyclodextrin-Conjugate Photodelivering Nitric Oxide with Fluorescence Reporting

Gábor Benkovics, Marta Perez-Lloret, Damien Afonso, András Darcsi, Szabolcs Béni, Éva Fenyvesi, Milo Malanga, Salvatore Sortino

Int. J. Pharm. acceptedhttps://doi.org/10.1016/j.ijpharm.2017.05.023

 

30. Design and evaluation of artificial receptors for the reversal of neuromuscular block

Tamás Sohajda, Ákos Fábián, Kata Tuza, Milo Malanga, Gábor Benkovics, Béla Fülesdi, Edömér Tassonyi, Lajos Szente

Int. J. Pharm. accepted, https://doi.org/10.1016/j.ijpharm.2017.03.060

 

29. Designed positively charged cyclodextrin hosts with enhanced binding of penicillins as carriers for the delivery of antibiotics: the case of oxacillin

M. Agnes, A. Thanassoulas, P. Stavropoulos, G. Nounesis, G. Miliotis, V. Miriagou, E. Athanasiou, G. Benkovics, M. Malanga, K. Yannakopoulou

Int. J. Pharm. accepted, doi.org/10.1016/j.ijpharm.2017.04.080

 

28. Novel β-cyclodextrin–eosin conjugates

Gábor Benkovics, Damien Afonso, András Darcsi, Szabolcs Béni, Sabrina Conoci, Éva Fenyvesi, Lajos Szente, Milo Malanga and Salvatore Sortino

 Beilstein J. Org. Chem. 2017, 13, 543–551.

 

27. Targeted Photodynamic Therapy with a Folate/Sensitizer Assembly Produced from Mesoporous Silica

Chunfang Zhou, Damien Afonso, Sabrina Valetti, Adam Feiler, Venera Cardile, Adriana C. E. Graziano, Sabrina Conoci and Salvatore Sortino

 Chem. Eur. J.DOI: chem.201701432R1

 

26. Mesoporous silica particles as a lipophilic drug vehicle investigated by fluorescence lifetime imaging

 

25. Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections

Valetti, S.; Xia, X.; Costa-Gouveia, J.; Brodin, P.; Bernet-Camard, M.-F.; Andersson, M.; Feiler, A., 

Nanomedicine 2017. doi:10.2217/nnm-2016-0364

 

24. How can nanoparticles contribute to antituberculosis therapy?

Costa-Gouveia J, Aínsa JA, Brodin P, Lucía A.

Drug Discov Today, 2017, Mar;22(3), 600-607 DOI: 10.1016/j.drudis.2017.01.011

 

23. Spontaneous Self-Assembly of Polymeric Nanoparticles in Aqueous Media: New Insights From Microfluidics, In Situ Size Measurements, and Individual Particle Tracking

Li X, Salzano G, Zhang J, Gref R

J. Pharm. Sci., 2017, 106(1), 395-401;http://dx.doi.org/10.1016/j.xphs.2016.09.024

 

22. The “visible” cyclodextrins: Synthesis and cell biological application of fluorescent-tagged cyclodextrins

Benkovics, G., Malanga, M., Fenyvesi, É.

Magyar Kémiai Folyóirat, 2016, 122(2-4), 76-82

 

21.Light-Regulated NO Release as a Novel Strategy To Overcome Doxorubicin Multidrug Resistance

K. Chegaev,  Aurore Fraix, Elena Gazzano,  Gamal Eldein F. Abd-Ellatef, M. Blangetti, B. Rolando, S. Conoci, C. Riganti, R. Fruttero, A. Gasco and S.  Sortino

ACS Med. Chem. Lett.   DOI:10.1021/acsmedchemlett.7b00016

 

20.Supramolecular activation of the photodynamic properties of porphyrinoid photosensitizers by calix[4]arene nanoassemblies

Ivana Di Bari, Aurore Fraix, Roberta Picciotto, Anna R. Blanco, Salvatore Petralia,Sabrina Conoci,  Giuseppe Granata, Grazia M. L. Consoli and Salvatore Sortino
RSC Adv., 2016, DOI: 10.1039/C6RA23492E.

 

19. Comparative evaluation of the chiral recognition potential of single-​isomer sulfated beta-cyclodextrinsynthesis intermediates in non-​aqueous capillary electrophoresis.
Fejos Ida; Darcsi Andras; Varga Erzsebet; Malanga Milo; Fenyvesi Eva; Sohajda Tamas; Szente Lajos; Benkovics Gabor; Beni Szabolcs
Journal of Chromatography A, Available online 15 July 2016, doi:10.1016/j.chroma.2016.07.033

18.Graphene oxide nanohybrid photoreleasing nitric oxide

Nino Marino, Salvatore Petralia, Marta Perez-Lloret, Jiri Mosinger, Sabrina Conoci  and Salvatore Sortino

J. Mater. Chem. B, 2016, 5825-5830, DOI:10.1039/C6TB01599A  

 

17. Single-isomer carboxymethyl-γ-cyclodextrin as chiral resolving agent for capillary electrophoresis

Gábor Benkovics, Ida Fejős, András Darcsi, Erzsébet Varga, Milo Malanga, Éva Fenyvesi, Tamás Sohajda, Lajos Szente, Szabolcs Béni, Julianna Szemán

J. Chromatogr. A,  accepted, Available online 1 July 2016

 

16. Photo-antimicrobial polymeric films releasing nitric oxide with fluorescent reporting under visible light

Nino Marino, Marta Perez-Lloret,Anna R. Blanco Alessandro Venuta, Fabiana Quagliaand Salvatore Sortino

J. Mater. Chem. B,accepted

 

15. A bactericidal calix[4]arene-based nanoconstruct with amplified NO photorelease

Ivana Di Bari, Roberta Picciotto, Giuseppe Granata, Anna R. Blanco,Grazia M. L. Consoliand Salvatore Sortino
Organic & Biomolecular Chemistry, accepted
 

14. New synthetic strategies for xanthene-dye-appended cyclodextrins  
M. Malanga, A. Darcsi, M. Balint, G. Benkovics, T. Sohajda, S. Beni  
Beilstein Journal of Organic Chemistry 2016, 12, 537-548. DOI: 10.3762/bjoc.12.53

13. Small is beautiful: Surprising nanoparticles

D. Duchêne, . Gref

Int. J.Pharm. 2016, 502(1), 219-231. doi.org/10.1016/j.ijpharm.2016.02.016

 

12. Effect of cyclodextrins on the degradation rate of benzylpenicillin
A.Popielec, E. Fenyvesi, K. Yannakopoulou and T. Loftsson
 Die PHARMAZIE2016, 71, 68–75. DOI: 10.1691/ph.2016.5114

 

11. Multilamellar Nanoparticles Self-Assembled from Opposite Charged Blends: Insights from Mesoscopic Simulation
S. Nie, X. Zhang, R. Gref, P. Couvreur, Y. Qian, L. Zhang

 

10. Polystyrene nanofiber materials for visible light-driven dual antibacterial action via simultaneous photogeneration
of NO and 1O2
J. Dolanský, P. Henke, P. Kubát, A. Fraix, S. Sortino and J. Mosinger
ACS Mater. Interf. Sci. DOI: 10.1021/acsami.5b06233

 

9. Towards an optimized treatment of intracellular bacteria infections: input of nanoparticulate drug delivery systems
C. Ladavière, R. Gref
Nanomedicine,DOI:10.2217/nnm.15.128 Invited review article.

 

8. Efficient “green” encapsulation of a highly hydrophilic anticancer drug in Metal-organic frameworks nanoparticles

V. Rodriguez-Ruiza, A. Maksimenko, R. Anand, S. Monti, V. Agostoni, P. Couvreur, M. Lampropoulou, K. Yannakopoulou, R. Gref

 J. Drug Targeting, 2015, 23(7-8), 759-767. DOI:10.3109/1061186X.2015.1073294Invited article in special issue honoring Prof. R. Langer for his lifetime achievements in the biomedical field.

 

7. Synthesis, characterization and photo-bactericidal activity of silanized xanthene-modified bacterial cellulose
membranes

H. Hettegger, M. Gorfer, S. Sortino, A. Fraix, D. Bandian, C. Rohrer,  W. Harreither, A. Potthast, T. Rosenau

Cellulose, Published online Sept 4, 2015. DOI 10.1007/s10570-015-0715-y

 

6. Anionic cyclodextrins as versatile hosts for pharmaceutical nanotechnology: Synthesis, drug delivery, enantioselectivity, contrast agents for MRI

I. M. Mavridis, K. Yannakopoulou

Int. J. Pharm. 2015, 492, 275-290.  doi:10.1016/j.ijpharm.2015.06.004. Mini-review

 

5. Cyclodextrins in the Battle against Antibiotic Resistant Microorganisms: Mimicking Cyclic Peptide Antibiotics

G. Benkovics

Cyclodextrin News 2015, 29(3), 1-7

 

4. Cyclodextrins, blood-brain barrier, and treatment of neurological diseases
M. Vecsernyés, F. Fenyvesi, I. Bácskay, M.A. Deli, L. Szente, E. Fenyvesi
Archives of Medical Research 2014, 45, 711-729 DOI: http://dx.doi.org/10.1016/j.arcmed.2014.11.020

 

3. A multicomponent gel for nitric oxide photorelease with fluorescent reporting
A. Fraix, N. Kandoth, R. Gref, and S. Sortino
Asian J. Org. Chem. 2015, 4(3), 256-261  DOI: 10.1002/ajoc.201402267

 

2.  A “green” strategy to construct non-covalent, stable and bioactive coatings on porous MOF nanoparticles
V. Agostoni, P. Horcajada, M. Noiray, M. Malanga, A. Aykaç, L. Jicsinszky, A. Vargas-Berenguel, N. Semiramoth, S. Daoud-Mahammed, V. Nicolas, C. Martineau, F. Taulelle, J. Vigneron, A. Etcheberry, C. Serre, R. Gref

 

1. Fighting against bacterial resistance to penicillins with CDs
 E. Fenyvesi